Back to Search
Start Over
Serum insulin, cortisol, leptin, neuropeptide Y, galanin and ghrelin levels in epileptic children receiving oxcarbazepine
- Source :
- European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. 15(6)
- Publication Year :
- 2010
-
Abstract
- Purpose The aim of this study was to investigate whether oxcarbazepine (OXC) monotherapy causes weight gain in epileptic children. Methods A total of 22 children with epilepsy (age 3.0–16.4 years) were assigned to OXC therapy. Serum levels of glucose, insulin, cortisol, leptin, neuropeptide Y (NPY), galanin and ghrelin were assessed before OXC therapy (month 0) and after the 6th and 18th months. Results There was no statistically significant difference in weight–standard deviation score (SDS), Height–SDS, BMI–SDS, serum glucose, insulin, cortisol, leptin, NPY, galanin and ghrelin levels between initial values (month 0) and those in the 6th and 18th months after OXC therapy (p > 0.05). Conclusions Our results indicate that OXC therapy causes neither weight change nor alterations in serum glucose, insulin, cortisol, leptin, NPY, galanin and ghrelin levels in children with epilepsy.
- Subjects :
- Blood Glucose
Male
medicine.medical_specialty
Adolescent
Hydrocortisone
medicine.medical_treatment
Oxcarbazepine
Galanin
Internal medicine
medicine
Humans
Insulin
Neuropeptide Y
Child
Epilepsy
business.industry
Leptin
digestive, oral, and skin physiology
Weight change
Body Weight
General Medicine
Neuropeptide Y receptor
Ghrelin
Endocrinology
Carbamazepine
Child, Preschool
Pediatrics, Perinatology and Child Health
Anticonvulsants
Female
Neurology (clinical)
business
hormones, hormone substitutes, and hormone antagonists
medicine.drug
Subjects
Details
- ISSN :
- 15322130
- Volume :
- 15
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
- Accession number :
- edsair.doi.dedup.....45a58e13feb73cb1407ea6fc7d770c0e