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DIFFERENT SHAPES OF MEGAKARYOCYTES IN ESSENTIAL THROMBOCYTHEMIA

Authors :
Maria, Faraz
Huma, Mansoori
Maria, Ali
Sidra Asad, Ali
Source :
Journal of Ayub Medical College Abbottabad. 34
Publication Year :
2022
Publisher :
Ayub Medical College, Abbottabad Pakistan, 2022.

Abstract

Essential thrombocytopenia is the myeloproliferative neoplasm associated with the JAK2/CALR/MPL mutation. It is characterized by an increase in thrombocytes and abnormal megakaryocytes. WHO established the diagnostic criteria for diagnosing the myeloproliferative disorder, which is the combination of molecular, clinical, and histological findings. The appearance of megakaryocytes on bone marrow biopsy is the distinguishing feature to identify myeloproliferative neoplasm, and this short review would like to emphasize the presentation of megakaryocytes in bone marrow biopsy.

Details

ISSN :
18192718 and 10259589
Volume :
34
Database :
OpenAIRE
Journal :
Journal of Ayub Medical College Abbottabad
Accession number :
edsair.doi.dedup.....459b75a4857c7fc663f122ef10f3de2c
Full Text :
https://doi.org/10.55519/jamc-02-9227