Biomedical Study of Demographics and Clinical Features of Lichen Planopilaris among the Iranian Population

Introduction: The demographic of Lichen PlanoPilaris (LPP) among the Iranian population is unknown. The aim of this study is to describe the clinical, demographic, and histopathologic findings of lichen planopilaris in the Iranian population. Method: In this cross-sectional study, all the patients with Lichen planopilaris were referred to the dermatology clinic of Imam Khomeini hospital from 2013 to 2015. Their demographic characteristics, drug histories, onset of disease, and family histories were obtained by written questionnaire. Additionally, this study employed SPSS v.20 as the statistical analysis software. Results: One hundred patients were enrolled in this study. With an average age of 47.11 years, 78% of the patients were female, and 50 of these were housewives. The patients included were often from Tehran with Fars ethnicity. Among these patients, 7 had alopecia areata skin disease, and 10 of them suffered from thyroid disease. Most of the histopathology samples collected from these biopsies revealed degeneration of the basal layer of the follicular structure, perifollicular fibrosis, inflammatory cells, and atrophy of the pilosebaceous structures. Conclusion: Both the age spectrum and the disease distribution of LPP among the Iranian population were very diverse when compared to previous studies.