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Group Refractive Index of Nanocrystalline Yttria-Stabilized Zirconia Transparent Cranial Implants
- Source :
- Frontiers in Bioengineering and Biotechnology, Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
- Publication Year :
- 2021
- Publisher :
- eScholarship, University of California, 2021.
-
Abstract
- Transparent “Window to the Brain” (WttB) cranial implants made from a biocompatible ceramic, nanocrystalline Yttria-Stabilized Zirconia (nc-YSZ), were recently reported. These reports demonstrated chronic brain imaging across the implants in mice using optical coherence tomography (OCT) and laser speckle imaging. However, optical properties of these transparent cranial implants are neither completely characterized nor completely understood. In this study, we measure optical properties of the implant using a swept source OCT system with a spectral range of 136 nm centered at 1,300 nm to characterize the group refractive index of the nc-YSZ window, over a narrow range of temperatures at which the implant may be used during imaging or therapy (20–43°C). Group refractive index was found to be 2.1–2.2 for OCT imaging over this temperature range. Chromatic dispersion for this spectral range was observed to vary over the sample, sometimes flipping signs between normal and anomalous dispersion. These properties of nc-YSZ should be considered when designing optical systems and procedures that propagate light through the window, and when interpreting OCT brain images acquired across the window.
- Subjects :
- Histology
Materials science
genetic structures
lcsh:Biotechnology
brain
Medical Biotechnology
Biomedical Engineering
Bioengineering
02 engineering and technology
01 natural sciences
cranial implant
010309 optics
chromatic dispersion
Optical coherence tomography
lcsh:TP248.13-248.65
0103 physical sciences
medicine
Cubic zirconia
Ceramic
Yttria-stabilized zirconia
optical coherence tomography
medicine.diagnostic_test
group refractive index
Neurosciences
Bioengineering and Biotechnology
imaging
Laser Speckle Imaging
Brief Research Report
021001 nanoscience & nanotechnology
Nanocrystalline material
eye diseases
window to the brain
visual_art
visual_art.visual_art_medium
Biomedical Imaging
Implant
Other Biological Sciences
0210 nano-technology
Refractive index
Biotechnology
Biomedical engineering
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Frontiers in Bioengineering and Biotechnology, Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
- Accession number :
- edsair.doi.dedup.....4554a7d1afe987f4ae71afad07c09bad