Chromosomal congenital anomalies and residence near hazardous waste landfill sites

Authors :: Martine Vrijheid
R Ide
I Fazarinc
Vera Nelen
Helen Dolk
Ben Armstrong
E. Garne
J. E. S. Scott
Fabrizio Bianchi
David H. Stone
Lenore Abramsky
Romano Tenconi
Elisabeth Robert
Source :: Vrijheid, M, Dolk, H, Armstrong, B, Abramsky, L, Bianchi, F, Fazarinc, I, Garne, E, Ide, R, Nelen, V, Robert, E, Scott, J E S, Stone, D & Tenconi, R 2002, ' Chromosomal congenital anomalies and residence near hazardous waste landfill sites ', Lancet, vol. 359, pp. 320-322 . https://doi.org/10.1016/s0140-6736(02)07531-1
Publication Year :: 2002
Publisher :: Elsevier BV, 2002.
Abstract: Previous findings of the EUROHAZCON study showed a 33% increase in risk of non-chromosomal anomalies near hazardous waste landfill sites. Here, we studied 245 cases of chromosomal anomalies and 2412 controls who lived near 23 such sites in Europe. After adjustment for confounding by maternal age and socioeconomic status, we noted a higher risk of chromosomal anomalies in people who lived close to sites (0-3 km) than in those who lived further away (3-7 km; odds ratio 1.41, 95% CI 1.00-1.99). Our results suggest an increase in risk of chromosomal anomalies similar to that found for non-chromosomal anomalies.

Tools