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Outcomes of left trisectionectomy and right hepatectomy for perihilar cholangiocarcinoma
- Source :
- HPB. 20:S685
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- Background Right hepatectomy (RH) is the standard surgical procedure for perihilar cholangiocarcinoma (PHC) with right-sided predominance in many centers. Although left trisectionectomy (LT) is aggressively performed for PHC with left-sided predominance in high-volume centers, the surgical and survival outcomes of LT are unclear. Therefore, this study aimed to compare the outcomes of LT and RH for PHC. Methods Consecutive patients who underwent surgical resection for PHC at Chiba University Hospital from 2008 to 2016 were retrospectively reviewed. The outcomes of patients with PHC who underwent LT were compared with those who underwent RH following one-to-one propensity score matching. Results Of 171 consecutive PHC resection patients, 111 were eligible for the study; 41 (37%) underwent LT, and 70 (63%) underwent RH. In a matched cohort (LT: n = 27, RH: n = 27), major complication rates (67% vs. 52%; p = 0.42), 90-day mortality rates (15% vs. 0%; p = 0.11) and R0 resection rates (56% vs. 44%; p = 0.58) were similar in both groups. The 3-year recurrence-free survival rates (27% vs. 47%; p = 0.27) and overall survival rates (45% vs. 60%; p = 0.17) were also similar in both groups. Conclusions In patients with PHC, LT could achieve similar surgical and survival outcomes as RH.
- Subjects :
- Male
medicine.medical_specialty
medicine.medical_treatment
030230 surgery
Cholangiocarcinoma
03 medical and health sciences
0302 clinical medicine
medicine
Hepatectomy
Humans
Major complication
Perihilar Cholangiocarcinoma
Propensity Score
Survival rate
Aged
Retrospective Studies
Hepatology
business.industry
Mortality rate
Gastroenterology
Retrospective cohort study
University hospital
Surgery
Survival Rate
Bile Ducts, Intrahepatic
Bile Duct Neoplasms
030220 oncology & carcinogenesis
Propensity score matching
Drainage
Female
business
Subjects
Details
- ISSN :
- 1365182X
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- HPB
- Accession number :
- edsair.doi.dedup.....44f53a59aa7d943a67ed3853f59f184e