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A Comparison of Angiogenesis and Glycolytic Imaging in Patients With Clinical Suspected Locally Advanced Breast Cancer
- Source :
- Clinical nuclear medicine. 44(8)
- Publication Year :
- 2019
-
Abstract
- F-FDG PET/CT imaging is an important diagnostic tool for accurate staging and assessment of response to neoadjuvant chemotherapy (NACT) in patients with locally advanced breast carcinoma (LABC). However, F-FDG being non-specific marker, it also accumulates in inflammatory conditions, leading to false positive results. Angiogenesis, an essential characteristic for tumor development, intrusion and metastasis can be imaged using Ga-labeled RGD tripeptide. We here depict a series of clinically staged LABC patients who underwent both Ga-DOTA-RGD2 and F-FDG PET/CT imaging for staging and illustrate the similarities and significant differences between the two tracers.
- Subjects :
- medicine.medical_specialty
Angiogenesis
medicine.medical_treatment
Locally advanced
Breast Neoplasms
030218 nuclear medicine & medical imaging
Metastasis
03 medical and health sciences
Intrusion
0302 clinical medicine
Breast cancer
Fluorodeoxyglucose F18
Positron Emission Tomography Computed Tomography
medicine
Humans
Radiology, Nuclear Medicine and imaging
In patient
Neoplasm Staging
Chemotherapy
Neovascularization, Pathologic
business.industry
General Medicine
Middle Aged
medicine.disease
030220 oncology & carcinogenesis
Female
Radiology
business
Breast carcinoma
Glycolysis
Subjects
Details
- ISSN :
- 15360229
- Volume :
- 44
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Clinical nuclear medicine
- Accession number :
- edsair.doi.dedup.....44b0a5bd6c12daf6c2c684d68987eb70