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Clinical significance of serum angiopoietin-1 in malignant peritoneal mesothelioma
- Source :
- Cancer investigation. 31(8)
- Publication Year :
- 2013
-
Abstract
- We have previously reported that angiopoietin-1 was correlated with pulmonary fibrosis. Here, we investigated the serum levels of angiopoietin-1 in patients with malignant peritoneal mesothelioma, which originate from mesenchymal cells similar to lung fibroblasts. We showed that patients with peritoneal mesothelioma had significantly higher serum levels of angiopoietin-1 in comparison with a population with a history of asbestos exposure without peritoneal mesothelioma, and the Kaplan-Meier method revealed a significant correlation between serum angiopoietin-1 levels and survival. This is the first report about the relationship between angiopoietin-1 and peritoneal mesothelioma.
- Subjects :
- Male
Mesothelioma
Cancer Research
Pathology
medicine.medical_specialty
Survival
Pulmonary Fibrosis
Population
medicine.disease_cause
Asbestos
Pulmonary fibrosis
medicine
Angiopoietin-1
Humans
Clinical significance
education
Peritoneal Neoplasms
Tumor marker
education.field_of_study
Lung
integumentary system
business.industry
General Medicine
Environmental exposure
Environmental Exposure
respiratory system
Middle Aged
medicine.disease
respiratory tract diseases
medicine.anatomical_structure
Oncology
Asbestosis
cardiovascular system
Peritoneal mesothelioma
Female
business
circulatory and respiratory physiology
Subjects
Details
- ISSN :
- 15324192
- Volume :
- 31
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Cancer investigation
- Accession number :
- edsair.doi.dedup.....44a7d4b389fa3e8d35a960b9da21af58