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Significance of delta agent infection in chronic hepatitis B virus infection: a study in British carriers
- Source :
- Gut. 24:1061-1063
- Publication Year :
- 1983
- Publisher :
- BMJ, 1983.
-
Abstract
- Delta antigen (delta) is a transmissible agent requiring hepatitis B virus (HBV) for its replication. Antibody to delta (anti-delta) was present in nine of 71 (13%) British HBV carriers: six were intravenous drug abusers and two were haemophiliacs. Anti-delta was negative in 30 HBsAg positive homosexuals. Cirrhosis was common in patients with anti-delta and those with anti-delta positive cirrhosis were significantly younger than those with anti-delta negative cirrhosis. In British HBV carriers delta infection is associated with intravenous drug abuse and haemophilia and perhaps a more rapid progression of chronic liver disease.
- Subjects :
- Adult
Male
HBsAg
Cirrhosis
Adolescent
Substance-Related Disorders
Hemophilia A
Haemophilia
Chronic liver disease
medicine.disease_cause
Virus
Hepatitis B Antigens
medicine
Humans
Hepatitis B Antibodies
Child
Aged
Hepatitis delta Antigens
Hepatitis B virus
Hepatitis B Surface Antigens
business.industry
Gastroenterology
Homosexuality
Middle Aged
Hepatitis B
medicine.disease
Virology
United Kingdom
Liver
Carrier State
Chronic Disease
Immunology
Female
Viral disease
business
Research Article
Subjects
Details
- ISSN :
- 00175749
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Gut
- Accession number :
- edsair.doi.dedup.....4479dddea50505864e7b74bf1dda982a