Preparation, biological evaluation and QSAR analysis of urea substituted 2,4-diamino-pyrimidine anti-malarials

Authors :: Borvornwat Toviwek
Jennifer Riley
Nicole Mutter
Mark Anderson
Lauren Webster
Irene Hallyburton
Duangkamol Gleeson
Kevin D. Read
M. Paul Gleeson
Source :: RSC Medicinal Chemistry. 13:1587-1604
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: Twenty six new phenylurea substituted 2,4-diamino-pyrimidines active against Plasmodium falciparum (Pf) 3D7 are reported.

Subjects :: Pharmacology
Organic Chemistry
Drug Discovery
Pharmaceutical Science
Molecular Medicine
Biochemistry

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