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Autophagy Involvement in Aseptic Loosening of Arthroplasty Components
- Source :
- Journal of Bone and Joint Surgery, American Volume, Journal of Bone and Joint Surgery, American Volume, Journal of Bone and Joint Surgery, Inc, 2019, 101 (5), pp.466-472. ⟨10.2106/JBJS.18.00479⟩, Journal of Bone and Joint Surgery, American Volume, 2019, 101 (5), pp.466-472. ⟨10.2106/JBJS.18.00479⟩
- Publication Year :
- 2019
- Publisher :
- HAL CCSD, 2019.
-
Abstract
- Aseptic loosening, the most common cause of arthroplasty component failure, is due to implant wear and subsequent release of biomaterial wear particles to the bone microenvironment, leading to a chronic inflammatory response.Autophagy, a cell-cleaning process allowing the degradation of damaged mate
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Aseptic loosening
Osteolysis
03 medical and health sciences
0302 clinical medicine
medicine
Autophagy
Humans
Orthopedics and Sports Medicine
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Arthroplasty, Replacement
ComputingMilieux_MISCELLANEOUS
030304 developmental biology
0303 health sciences
Osteoblasts
business.industry
Macrophages
General Medicine
Arthroplasty
Surgery
Prosthesis Failure
030211 gastroenterology & hepatology
Implant
business
Forecasting
Subjects
Details
- Language :
- English
- ISSN :
- 00219355 and 15351386
- Database :
- OpenAIRE
- Journal :
- Journal of Bone and Joint Surgery, American Volume, Journal of Bone and Joint Surgery, American Volume, Journal of Bone and Joint Surgery, Inc, 2019, 101 (5), pp.466-472. ⟨10.2106/JBJS.18.00479⟩, Journal of Bone and Joint Surgery, American Volume, 2019, 101 (5), pp.466-472. ⟨10.2106/JBJS.18.00479⟩
- Accession number :
- edsair.doi.dedup.....445c1373966f081da43f725287e8ea58