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Multiple Arterial Thrombosis in a 78-Year-Old Patient: Catastrophic Thrombotic Syndrome in COVID-19

Authors :
Mihaela Calcaianu
Bree Lawson
Nicolas Girerd
Patrick Allimant
David Kenizou
Marine Kinnel
Beatrice Morisset
Ines Harzallah
Didier Bresson
L. Jacquemin
Clemence Perrin
Stéphane Zuily
BOZEC, Erwan
Centre Hospitalier Emile Muller [Mulhouse] (CH E.Muller Mulhouse)
Groupe Hospitalier de Territoire Haute Alsace (GHTHA)
Service Hématologie, Mulhouse
Groupe Hospitalier de Territoire Haute Alsace (GHTHA)-Groupe Hospitalier de Territoire Haute Alsace (GHTHA)
Défaillance Cardiovasculaire Aiguë et Chronique (DCAC)
Université de Lorraine (UL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)
Centre d'investigation clinique plurithématique Pierre Drouin [Nancy] (CIC-P)
Centre d'investigation clinique [Nancy] (CIC)
Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Cardiovascular and Renal Clinical Trialists [Vandoeuvre-les-Nancy] (INI-CRCT)
Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy]
French-Clinical Research Infrastructure Network - F-CRIN [Paris] (Cardiovascular & Renal Clinical Trialists - CRCT )
Source :
Canadian Journal of Cardiology (CJC) : official journal of the Canadian Cardiovascular Society (CCS), Canadian Journal of Cardiology (CJC) : official journal of the Canadian Cardiovascular Society (CCS), ScienceDirect-Elsevier, 2021, 3 (2), pp.198-200. ⟨10.1016/j.cjco.2020.09.020⟩, CJC Open
Publication Year :
2021
Publisher :
HAL CCSD, 2021.

Abstract

International audience; We describe a patient with coronavirus disease 2019 (COVID-19) and multiple concomitant thromboses occurring on the 9th day of hospital stay. Thromboses were found in distinct zones of the aorta, as well as in the renal, humeral, and pulmonary arteries. The extensive biological workup performed following this catastrophic thrombotic syndrome found no evidence for underlying prothrombotic disease. In light of current evidence regarding endothelium abnormalities related to COVID-19, this extreme case of catastrophic thrombotic syndrome suggests that COVID-19 can induce severe arterial thrombosis following intense endothelial activation.

Details

Language :
English
ISSN :
2589790X
Database :
OpenAIRE
Journal :
Canadian Journal of Cardiology (CJC) : official journal of the Canadian Cardiovascular Society (CCS), Canadian Journal of Cardiology (CJC) : official journal of the Canadian Cardiovascular Society (CCS), ScienceDirect-Elsevier, 2021, 3 (2), pp.198-200. ⟨10.1016/j.cjco.2020.09.020⟩, CJC Open
Accession number :
edsair.doi.dedup.....443bdfeef958067ea5e9aa35f8ab1d48
Full Text :
https://doi.org/10.1016/j.cjco.2020.09.020⟩