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Trends in methadone-related deaths in Zurich
- Source :
- International Journal of Legal Medicine. 124:381-385
- Publication Year :
- 2010
- Publisher :
- Springer Science and Business Media LLC, 2010.
-
Abstract
- Methadone has a long and successful history in the treatment of opioid addiction. In recent years, it has become popular again--as potent and inexpensive analgesic in patients with chronic pain. Since methadone has been used fatalities have been reported. In our study all methadone-associated deaths in Zurich from 1998 to 2007 were analysed. Most of the 146 detected deaths of the past 10 years occurred during substitution programmes or illicit intake of methadone while only three of them could be attributed to methadone used as an analgesic. Noticeable in our study was the high percentage of cases of combined drug intoxication (76%). The most frequent co-intoxicants were alcohol and cocaine. Mortalities attributed to methadone intoxication alone were a rare finding and could only be detected in five cases of deceased who had received methadone maintenance treatment. The aim of our study is to assess the trends in the number and nature of methadone-related fatalities in Zurich during the last 19 years. For this purpose a previous study from Zurich (1989-1997) was included, whereby a very long observation period and large number of cases resulted.
- Subjects :
- Adult
Male
Narcotics
Methadone maintenance
Pediatrics
medicine.medical_specialty
Adolescent
Substance-Related Disorders
Analgesic
Observation period
Gas Chromatography-Mass Spectrometry
Pathology and Forensic Medicine
Benzodiazepines
Forensic Toxicology
Age Distribution
Cocaine
Cause of Death
Opiate Substitution Treatment
Humans
Medicine
In patient
Sex Distribution
Opioid addiction
Ethanol
business.industry
Chronic pain
Central Nervous System Depressants
Middle Aged
medicine.disease
Suicide
Anesthesia
Female
Drug intoxication
business
Methadone
Switzerland
medicine.drug
Subjects
Details
- ISSN :
- 14371596, 09379827, and 19891997
- Volume :
- 124
- Database :
- OpenAIRE
- Journal :
- International Journal of Legal Medicine
- Accession number :
- edsair.doi.dedup.....440629312fa9402f94edd5b25aeb2594