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Safety and on-treatment efficacy of telaprevir: the early access programme for patients with advanced hepatitis C
- Source :
- Gut
- Publication Year :
- 2013
- Publisher :
- BMJ, 2013.
-
Abstract
- Severe adverse events (AEs) compromise the outcome of direct antiviral agent-based treatment in patients with advanced liver fibrosis due to HCV infection. HEP3002 is an ongoing multinational programme to evaluate safety and efficacy of telaprevir (TVR) plus pegylated-interferon-α (PEG-IFNα) and ribavirin (RBV) in patients with advanced liver fibrosis caused by HCV genotype 1 (HCV-1).<br />JOURNAL ARTICLE<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published
- Subjects :
- Adult
Liver Cirrhosis
Male
medicine.medical_specialty
Cirrhosis
Genotype
Alpha interferon
Hepacivirus
Interferon alpha-2
Antiviral Agents
Gastroenterology
Drug Administration Schedule
Polyethylene Glycols
Telaprevir
chemistry.chemical_compound
Internal medicine
Ribavirin
medicine
Humans
Prospective Studies
Aged
business.industry
Interferon-alpha
virus diseases
Hepatitis C
Hepatitis C, Chronic
Middle Aged
Sciences bio-médicales et agricoles
medicine.disease
Rash
Recombinant Proteins
digestive system diseases
Surgery
Discontinuation
Treatment Outcome
Tolerability
chemistry
Multivariate Analysis
Linear Models
Drug Therapy, Combination
Female
medicine.symptom
business
Oligopeptides
Follow-Up Studies
medicine.drug
Subjects
Details
- ISSN :
- 14683288 and 00175749
- Volume :
- 63
- Database :
- OpenAIRE
- Journal :
- Gut
- Accession number :
- edsair.doi.dedup.....4401a1a5cdcc43f1ae9e72fd59ad5940