The role of the T3 molecular complex in antigen recognition and subsequent activation events

Monoclonal antibodies raised against human T lymphocytes have identified several cell surface structures that are intimately involved in T-cell function. Perhaps the most familiar is the structure labelled T3. First identified as an antigen five years ago, it is now known to be a complex of at least three molecular species that is found on all T lymphocytes. There seems little doubt that T3 is closely associated with the antigen receptor on these cells, but how? A new (and different) answer is proposed in each of the following articles.