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Associations between Serum Apelin-12 Levels and Obesity-Related Markers in Chinese Children
- Source :
- PLoS ONE, Vol 9, Iss 1, p e86577 (2014), PLoS ONE
- Publication Year :
- 2014
- Publisher :
- Public Library of Science (PLoS), 2014.
-
Abstract
- Objective To investigate possible correlations between apelin-12 levels and obesity in children in China and associations between apelin-12 and obesity-related markers, including lipids, insulin sensitivity and insulin resistance index (HOMA-IR). Methods Forty-eight obese and forty non-obese age- and gender-matched Chinese children were enrolled between June 2008 and June 2009. Mean age was 10.42±2.03 and 10.86±2.23 years in obesity and control groups, respectively. Main outcome measures were apelin-12, BMI, lipids, glucose and insulin. HOMA-IR was calculated for all subjects. Results All obesity group subjects had significantly higher total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), insulin levels and HOMA-IR (all P
- Subjects :
- Blood Glucose
Male
Anatomy and Physiology
medicine.medical_treatment
lcsh:Medicine
Biochemistry
Pediatrics
Body Mass Index
chemistry.chemical_compound
Pathology
Insulin
Child
lcsh:Science
Multidisciplinary
Anthropometry
Lipids
Apelin
Medicine
Intercellular Signaling Peptides and Proteins
Female
Research Article
medicine.medical_specialty
Endocrine System
Biology
Statistics, Nonparametric
Childhood obesity
Sex Factors
Insulin resistance
Adolescent Medicine
Asian People
Diagnostic Medicine
Internal medicine
medicine
Humans
Obesity
Nutrition
Plasma Proteins
Endocrine Physiology
Cholesterol
lcsh:R
Proteins
Lipid Metabolism
medicine.disease
Endocrinology
chemistry
lcsh:Q
Insulin Resistance
Body mass index
Biomarkers
General Pathology
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....43d47fd309a714f3ea22e5811afff2e7