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A systematic review of recommendations on screening strategies for breast cancer due to hereditary predisposition: Who, When, and How?
- Source :
- Cancer Medicine, Vol 10, Iss 10, Pp 3437-3448 (2021), Cancer Medicine
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background Breast cancer is a global health problem that cannot be underestimated. Many studies have shown that breast cancer is related to pathogenic mutations in hereditary predisposition genes. Clinical practice guidelines play a vital role in guiding the selection of breast cancer screening. Little is known about the quality and consistency of guidelinesā recommendations and their changes over these years. Methods We reviewed the existing screening guidelines for genetic susceptibility to breast cancer and assessed the methodological quality, and summarized the recommendations to aid clinicians to make decisions. We conducted a systematic search in PubMed, Embase, Web of Science, and guidelineāspecific databases, aiming to find the guidelines of breast cancer due to hereditary predisposition. The necessary information was exacted by Excel. We also summarized different evidence grading systems. The qualities of the guidelines were assessed by the Appraisal of Guidelines Research and Evaluation II (AGREE II) instrument. Results A total of 54 recommendations from 13 guidelines were extracted. Generally speaking, the recommendations were consistent, mainly focusing on mammography and MRI. Conclusions The recommendations differ in details. Moreover, different guidelines are based on different grading systems, and some guidelines are not divided for age limits, which may limit the promotion and implementation of the guidelines. It is suggested that improvement can be made in this regard in the future.<br />Systematic and comprehensive search of breast cancer gene mutation screening guidelines, and summarize and analyze the recommendations, to find out the current problems
- Subjects :
- 0301 basic medicine
Cancer Research
medicine.medical_specialty
Databases, Factual
media_common.quotation_subject
Breast Neoplasms
Review
03 medical and health sciences
Breast cancer screening
breast cancer
0302 clinical medicine
Breast cancer
Promotion (rank)
medicine
Genetic predisposition
Global health
Humans
Mass Screening
Mammography
Genetic Predisposition to Disease
genetic mutated
Radiology, Nuclear Medicine and imaging
Grading (tumors)
Early Detection of Cancer
RC254-282
media_common
medicine.diagnostic_test
business.industry
screening
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Guideline
AGREE II
medicine.disease
030104 developmental biology
Oncology
030220 oncology & carcinogenesis
Family medicine
Female
business
Cancer Prevention
guideline
Subjects
Details
- ISSN :
- 20457634
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Cancer Medicine
- Accession number :
- edsair.doi.dedup.....43d42904a94ab742571d455c597f9e77