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In Vivo Dosimetry With a Linear MOSFET Array to Evaluate the Urethra Dose During Permanent Implant Brachytherapy Using Iodine-125
- Source :
- International Journal of Radiation Oncology*Biology*Physics. 75:1266-1272
- Publication Year :
- 2009
- Publisher :
- Elsevier BV, 2009.
-
Abstract
- Purpose To develop a technique to monitor the dose rate in the urethra during permanent implant brachytherapy using a linear MOSFET array, with sufficient accuracy and without significantly extending the implantation time. Methods and Materials Phantom measurements were performed to determine the optimal conditions for clinical measurements. In vivo measurements were performed in 5 patients during the 125 I brachytherapy implant procedure. To evaluate if the urethra dose obtained in the operating room with the ultrasound transducer in the rectum and the patient in treatment position is a reference for the total accumulated dose; additional measurements were performed after the implantation procedure, in the recovery room. Results In vivo measurements during and after the implantation procedure agree very well, illustrating that the ultrasound transducer in the rectum and patient positioning do not influence the measured dose in the urethra. In vivo dose values obtained during the implantation are therefore representative for the total accumulated dose in the urethra. In 5 patients, the dose rates during and after the implantation were below the maximum dose rate of the urethra, using the planned seed distribution. Conclusion In vivo dosimetry during the implantation, using a MOSFET array, is a feasible technique to evaluate the dose in the urethra during the implantation of 125 I seeds for prostate brachytherapy.
- Subjects :
- Male
Cancer Research
Maximum Tolerated Dose
Urinary system
medicine.medical_treatment
Brachytherapy
Imaging phantom
Iodine Radioisotopes
Urethra
Prostate
medicine
Humans
Dosimetry
Radiology, Nuclear Medicine and imaging
Radiometry
Radiation
Phantoms, Imaging
business.industry
Rectum
Prostatic Neoplasms
Equipment Design
Radiation therapy
medicine.anatomical_structure
Oncology
Calibration
Feasibility Studies
Nuclear medicine
business
Prostate brachytherapy
Subjects
Details
- ISSN :
- 03603016
- Volume :
- 75
- Database :
- OpenAIRE
- Journal :
- International Journal of Radiation Oncology*Biology*Physics
- Accession number :
- edsair.doi.dedup.....43ac262da5e72841797cb58f1bee07e7