HG-68COMBINED ALTERATIONS IN MAPK PATHWAY GENES, CDKN2A/B AND ATRX CHARACTERIZE ANAPLASTIC PILOCYTIC ASTROCYTOMA

Authors :: Martina Deckert
Hildegard Dohmen-Scheufler
Andreas von Deimling
Albert J. Becker
Ulrich W. Thomale
Werner Paulus
Jens Schittenhelm
Caterina Giannini
Almuth F. Keßler
Wolf Mueller
Michael Weller
Sebastian Brandner
David T.W. Jones
Patricia Kohlhof
Christian Mawrin
Amulya NageswaraRao
Camelia M. Monoranu
Christian Hartmann
Muin S. A. Tuffaha
Stefan M. Pfister
Ute Pohl
Dorothee Gramatzki
Kristin Huang
Adriana Olar
David Reuß
Ekkehard Hewer
Fausto J. Rodriguez
Christian Kölsche
David Capper
Rolf Buslei
Marco Prinz
Jörg Felsberg
Annika K. Wefers
Annekathrin Kratz
Katharina Heß
Ori Staszewski
Till Acker
Volkmar Hans
Guido Reifenberger
Arend Koch
Volker Hovestadt
Daniel Schrimpf
Benjamin Brokinkel
Felix Sahm
Source :: Neuro-Oncology. 18:iii63.2-iii63
Publication Year :: 2016
Publisher :: Oxford University Press (OUP), 2016.
Abstract: Introduction: Tumors with histological features of pilocytic astrocytoma but with increased mitotic activity and additional high grade features (i.e. microvascular proliferation, necrosis) have been designated anaplastic pilocytic astrocytomas (APA). Patients with such tumors are thought to have an [for full text, please go to the a.m. URL]

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