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Clinical Characteristics and Outcome of Drug‐Induced Liver Injury in the Older Patients: From the Young‐Old to the Oldest‐Old
- Source :
- Clinical Pharmacology and Therapeutics, 109, 4, pp. 1147-1158, RIUMA. Repositorio Institucional de la Universidad de Málaga, instname, Clinical Pharmacology and Therapeutics, 109, 1147-1158
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Old patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. We sought for the distinctive characteristics of DILI in older patients across age groups. A total of 882 DILI patients included in the Spanish DILI Registry (33% ≥65 years) were categorized according to age: “young” (
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Hígado - Enfermedades
Comorbidity
elderly
Severity of Illness Index
030226 pharmacology & pharmacy
Culprit
oldest-old
Young Adult
03 medical and health sciences
Liver disease
Sex Factors
0302 clinical medicine
Levofloxacin
Internal medicine
medicine
Humans
Pharmacology (medical)
Ticlopidine
Child
Aged
Aged, 80 and over
Pharmacology
Polypharmacy
business.industry
Age Factors
Odds ratio
Middle Aged
Jaundice
medicine.disease
mortality
lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]
Spain
030220 oncology & carcinogenesis
comorbitity
Female
Chemical and Drug Induced Liver Injury
medicine.symptom
business
drug-induced liver injury
Cholestatic
medicine.drug
Subjects
Details
- ISSN :
- 15326535, 00099236, and 11471158
- Volume :
- 109
- Database :
- OpenAIRE
- Journal :
- Clinical Pharmacology & Therapeutics
- Accession number :
- edsair.doi.dedup.....4343f3e3548bb6318764b253e03bca4b
- Full Text :
- https://doi.org/10.1002/cpt.2108