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Factors associated with healing of diabetes-related foot ulcers: Observations from a large prospective real-world cohort
- Source :
- Diabetes care, 44(7), e143-e145. American Diabetes Association Inc.
- Publication Year :
- 2021
-
Abstract
- Diabetes-related foot ulcers (DFUs) affect around 20 million people annually and are a leading cause of the global disability burden (1). DFUs are complex to treat, take months to heal, result in poorer quality of life, and place patients at high risk of hospitalization and amputation. Thus, understanding the influence that different factors have on healing of DFUs is vital. Various demographic, comorbidity, limb, ulcer, and treatment-related factors associated with healing of DFUs have been identified from cohorts attending mostly metropolitan tertiary centers (2–4). However, very few studies have prospectively investigated the influence that these and other factors have on healing in more real-world DFU cohorts attending geographically diverse secondary and tertiary centers. Therefore, we aimed to investigate the influence of 34 factors on healing in a large real-world DFU cohort. We prospectively examined 4,832 consecutive patients with DFU(s) that presented for their first visit to 1 of 65 secondary or tertiary diabetic foot services, across 15 of 17 regions in Queensland (Australia), between July 2011 and December 2017. A DFU was defined as a full-thickness wound below the ankle on a person with diabetes. For DFU clinical and research purposes, foot-related health professionals using the Queensland High Risk Foot Form (QHRFF) directly examined each patient clinically at their first (and subsequent) visit for 4 demographic, 9 comorbidity, 6 limb, 3 ulcer, and 12 treatment factors (5). For those with multiple DFUs, we used the most severe score for each factor and the combined ulcer size from all DFUs (5). Factors from the first visit were used as the baseline. Subsequent visit examinations determined if the DFU(s) healed, …
- Subjects :
- medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
Cohort Studies
Quality of life
Internal medicine
Diabetes mellitus
Diabetes Mellitus
Internal Medicine
medicine
Humans
Prospective Studies
Advanced and Specialized Nursing
Wound Healing
business.industry
medicine.disease
R1
Comorbidity
Diabetic foot
Diabetic Foot
medicine.anatomical_structure
Amputation
Cohort
Ankle
business
Foot (unit)
Subjects
Details
- Language :
- English
- ISSN :
- 01495992
- Volume :
- 44
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Diabetes care
- Accession number :
- edsair.doi.dedup.....42f88195d985abaac473a43aeea31ccb