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Photostable near-infrared-absorbing diradical-platinum(<scp>ii</scp>) complex solubilized by albumin toward a cancer photothermal therapy agent

Authors :
Ryota Sawamura
Masataka Sato
Nobuhiko Iki
Atsuko Masuya-Suzuki
Source :
RSC Advances. 10:6460-6463
Publication Year :
2020
Publisher :
Royal Society of Chemistry (RSC), 2020.

Abstract

A hydrophobic diradical-platinum(ii) complex was solubilized in aqueous solutions by using bovine serum albumin and exhibited photothermal conversion under near-infrared (NIR) light irradiation. The complex was introduced into cancer cells and induced cell death upon absorption of NIR. These results imply that the complex can function as a photothermal therapeutic agent.

Details

ISSN :
20462069
Volume :
10
Database :
OpenAIRE
Journal :
RSC Advances
Accession number :
edsair.doi.dedup.....42c19ad55da4b5da8b8bbd474f9a858e