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Luminescent magnetic quantum dots for in vitro/in vivo imaging and applications in therapeutics
- Source :
- Journal of nanoscience and nanotechnology. 13(6)
- Publication Year :
- 2013
-
Abstract
- The quest for design of newer/advanced methods for medical diagnosis and targeted therapeutics are of utmost interest and challenging too, because of its importance in clinical diagnosis. Currently available diagnosis methodologies have their own disadvantages. These shortcomings can be overcome by using multimodal imaging systems where two or more imaging modalities may be coupled. Nanoparticles being widely studied for targeted drug delivery and as biological contrasting agents, might play a decisive role in such findings. This review is focused towards the ongoing research in the area of hybrid nanocomposites which can be used for both as MRI contrasting agent (magnetic nanoparticles) and molecular imaging studies (using fluorescent quantum dots) at in vitro and in vivo level. Though several reports are available in literature for such bimodal imaging systems, their clinical trials are very restricted, possibly because of the lack of communication between the in vitro and in vivo studies. This review is expected to bridge the gap between such studies.
- Subjects :
- Materials science
Luminescence
In Vitro Techniques
Biomedical Engineering
Bioengineering
Nanotechnology
General Chemistry
Therapeutics
Condensed Matter Physics
Magnetic Resonance Imaging
Magnetics
Targeted drug delivery
Microscopy, Electron, Transmission
Quantum dot
In vivo
Clinical diagnosis
Quantum Dots
General Materials Science
In vitro in vivo
Medical diagnosis
Molecular imaging
Subjects
Details
- ISSN :
- 15334880
- Volume :
- 13
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Journal of nanoscience and nanotechnology
- Accession number :
- edsair.doi.dedup.....424d20f859cfea65001095628d795e90