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In-line phase-contrast breast tomosynthesis: A phantom feasibility study at a synchrotron radiation facility
- Source :
- Physics in Medicine and Biology
- Publication Year :
- 2016
-
Abstract
- The major objective is to adopt, apply and test developed in-house algorithms for volumetric breast reconstructions from projection images, obtained in in-line phase-contrast mode. Four angular sets, each consisting of 17 projection images obtained from four physical phantoms, were acquired at beamline ID17, European Synchroton Radiation Facility, Grenoble, France. The tomosynthesis arc was ±32°. The physical phantoms differed in complexity of texture and introduced features of interest. Three of the used phantoms were in-house developed, and made of epoxy resin, polymethyl-methacrylate and paraffin wax, while the fourth phantom was the CIRS BR3D. The projection images had a pixel size of 47 μm × 47 μm. Tomosynthesis images were reconstructed with standard shift-and-add (SAA) and filtered backprojection (FBP) algorithms. It was found that the edge enhancement observed in planar x-ray images is preserved in tomosynthesis images from both phantoms with homogeneous and highly heterogeneous backgrounds. In case of BR3D, it was found that features not visible in the planar case were well outlined in the tomosynthesis slices. In addition, the edge enhancement index calculated for features of interest was found to be much higher in tomosynthesis images reconstructed with FBP than in planar images and tomosynthesis images reconstructed with SAA. The comparison between images reconstructed by the two reconstruction algorithms shows an advantage for the FBP method in terms of better edge enhancement. Phase-contrast breast tomosynthesis realized in in-line mode benefits the detection of suspicious areas in mammography images by adding the edge enhancement effect to the reconstructed slices.
- Subjects :
- Radiology, Nuclear Medicine and Imaging
breast tomosynthesi
FIS/07 - FISICA APPLICATA (A BENI CULTURALI, AMBIENTALI, BIOLOGIA E MEDICINA)
Synchrotron radiation
phase-contrast
Imaging phantom
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Planar
filtered backprojection
breast tomosynthesis
medicine
Mammography
Humans
Computer vision
Microscopy, Phase-Contrast
Breast
Projection (set theory)
Physics
Pixel
medicine.diagnostic_test
Radiological and Ultrasound Technology
business.industry
Phantoms, Imaging
shift-and-add reconstruction
Medicine (all)
Edge enhancement
Tomosynthesis
inhomogeneous background
030220 oncology & carcinogenesis
Feasibility Studies
Female
Artificial intelligence
business
Algorithms
Synchrotrons
Subjects
Details
- Language :
- English
- ISSN :
- 00319155 and 00223727
- Database :
- OpenAIRE
- Journal :
- Physics in Medicine and Biology
- Accession number :
- edsair.doi.dedup.....424800739192db97ef8c3bbf611d4eb4