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Microbiological diagnostics of inneriotrobic infections
- Source :
- Klinicheskaia laboratornaia diagnostika. 65(10)
- Publication Year :
- 2020
-
Abstract
- Intrauterine infections - infectious diseases in which infection of the fetus occurred in the ante- or intrapartum period, accompanied by clinical manifestations. The purpose of this study was to study the information content and diagnostic significance of the microbiological research method for the etiological diagnosis of intrauterine infections of a bacterial nature. A retrospective (2011-2014) and prospective (2015-2019) analysis of the results of microbiological studies of biomaterials from puerperas and their newborns was carried out in 63 cases of early neonatal mortality with established diagnoses of intrauterine infections. In the study of the separated cervical canal, placenta samples, and amniotic fluid, seeding of coagulase-negative staphylococci was most frequently observed, among which the species Staphylococcus epidermidis dominated, Staphylococcus hominis, Staphylococcus haemolyticus, Staphylococcus warneri also met. Frequent isolation of group B streptococci from the placenta and amniotic fluid was revealed in comparison with the material from the cervical canal.The information content of the microbiological study of materials from the puerpera and the newborn in terms of confirmation of the pathogen and the fact of its transmission from mother to fetus/newborn does not exceed 30%. Even with high contamination of the genital tract of the puerpera, placenta or amniotic fluid, examination of the materials from the newborn immediately after birth often does not allow to identify the causative agent, probably due to the low degree of contamination at the initial stage of development of the infectious process. An increase in the diagnostic value of microbiological research can be facilitated by an increase in the frequency of examinations, the number of samples taken; the use of techniques to increase the sensitivity of cultural research at the stage of analysis; the use of molecular genetic methods, especially in the study of materials from newborns.
- Subjects :
- Coagulase
medicine.medical_specialty
Amniotic fluid
Staphylococcus
01 natural sciences
010104 statistics & probability
03 medical and health sciences
0302 clinical medicine
Staphylococcus epidermidis
Pregnancy
Placenta
Staphylococcus hominis
medicine
Humans
030212 general & internal medicine
Prospective Studies
0101 mathematics
Retrospective Studies
Fetus
biology
Obstetrics
business.industry
Biochemistry (medical)
Infant, Newborn
General Medicine
Staphylococcal Infections
biology.organism_classification
Staphylococcus haemolyticus
Medical Laboratory Technology
medicine.anatomical_structure
Staphylococcus warneri
Etiology
Female
business
Subjects
Details
- ISSN :
- 08692084
- Volume :
- 65
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Klinicheskaia laboratornaia diagnostika
- Accession number :
- edsair.doi.dedup.....422a28f37778cd3c6481f0a97679c830