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PLA/ β-TCP complex tubes: the mechanical properties and applications of artificial bone
- Source :
- Journal of biomaterials science. Polymer edition. 23(13)
- Publication Year :
- 2011
-
Abstract
- Poly(lactic acid) (PLA) twisted yarn was braided into a 6-layered, hollow, cylindrical braid on a 16-spindle braid machine. The PLA braid was then placed inside a β-TCP tube, forming the PLA/β-TCP complex tube which imitates the porous structure of sponge bone. Different components and structures were studied to determine the best bone molding material. The β-TCP tube was created by sintering TCP powder mixed with stearic acid in a ratio of 1:1.5 to form a highly porous and well-structured tube with interconnected pores; its resulting porosity was 85.8 ± 0.93%. The PLA/β-TCP complex tube was implanted in a rabbit’s femur and after 3 months a marrow cavity was discovered at the tube’s core. New bone was also observed, regenerating around the PLA braid within the PLA/β-TCP complex tube.
- Subjects :
- Calcium Phosphates
Artificial bone
Materials science
Bone Regeneration
Cell Survival
Polymers
Polyesters
Biomedical Engineering
Biophysics
Sintering
Bioengineering
Core (manufacturing)
Molding (process)
Biomaterials
chemistry.chemical_compound
stomatognathic system
Cell Line, Tumor
Materials Testing
Braid
Animals
Humans
Tube (fluid conveyance)
Femur
Lactic Acid
Composite material
Porosity
Tissue Engineering
technology, industry, and agriculture
equipment and supplies
Coculture Techniques
Disease Models, Animal
chemistry
Bone Substitutes
Microscopy, Electron, Scanning
lipids (amino acids, peptides, and proteins)
Stearic acid
Rabbits
Stearic Acids
Subjects
Details
- ISSN :
- 15685624
- Volume :
- 23
- Issue :
- 13
- Database :
- OpenAIRE
- Journal :
- Journal of biomaterials science. Polymer edition
- Accession number :
- edsair.doi.dedup.....42264a548f1988cbb3270f7d05c85bde