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Glycolipids and complete Freund's adjuvant cause insulitis in rats
- Source :
- Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 23(3)
- Publication Year :
- 1991
-
Abstract
- Gangliosides are considered to be the antigenic component reacting with islet cell antibodies which are one of the serological hallmarks of type 1 diabetes mellitus. We therefore imminized rats with glycolipids and Freund's adjuvant and we then studied the histology of the pancreas and the metabolic status in parallel with the development of insulitis
- Subjects :
- Male
medicine.medical_specialty
endocrine system diseases
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
Clinical Biochemistry
Freund's Adjuvant
Biochemistry
Islets of Langerhans
Endocrinology
Glycolipid
Antigen
Reference Values
Internal medicine
medicine
Animals
Inflammation
geography
geography.geographical_feature_category
Ganglioside
biology
business.industry
Biochemistry (medical)
Pancreatic Diseases
Rats, Inbred Strains
General Medicine
Islet
medicine.disease
Rats
Freund's adjuvant
Rats, Inbred Lew
Immunology
biology.protein
Antibody
Glycolipids
business
Insulitis
Adjuvant
Subjects
Details
- ISSN :
- 00185043
- Volume :
- 23
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
- Accession number :
- edsair.doi.dedup.....41ebdad10ccf74e9954138e82f982873