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Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters
- Source :
- Chemical Communications. 47:3514
- Publication Year :
- 2011
- Publisher :
- Royal Society of Chemistry (RSC), 2011.
-
Abstract
- SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.
- Subjects :
- Surface Properties
Nanotechnology
Cell Separation
Spectrum Analysis, Raman
Photochemistry
Antibodies
Catalysis
symbols.namesake
chemistry.chemical_compound
Cell Line, Tumor
Materials Chemistry
Humans
Multiplex
Cyanine
Coloring Agents
Chemistry
Metals and Alloys
General Chemistry
Carbocyanines
Single excitation
Nanostructures
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Cancer cell
Ceramics and Composites
symbols
Spectrum analysis
Peptides
Raman spectroscopy
Subjects
Details
- ISSN :
- 1364548X and 13597345
- Volume :
- 47
- Database :
- OpenAIRE
- Journal :
- Chemical Communications
- Accession number :
- edsair.doi.dedup.....41e42901ca7fe1af341d6484a7dd3d4b