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Nosocomial Candida parapsilosis candidaemia: risk factors, antifungal susceptibility and outcome
- Source :
- Journal of Hospital Infection. 87:54-58
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- A retrospective analysis was undertaken from 2000 to 2010 to show the risk factors associated with death within 30 days in patients with C. parapsilosis candidaemia (CPC). Fifty-one cases of nosocomial CPC were included in the analysis. All isolates from blood cultures were susceptible to micafungin and fluconazole. The overall mortality rate was 23.5%, and the most severe complications were endocarditis (5.9%) and endophthalmitis (5.9%). On multi-variate analysis, APACHE II score >25 (odds ratio 43.9) and retained cardiovascular prosthetic materials (RCPM) (prosthetic valve or graft) (odds ratio 14.6) were found to be risk factors associated with death. Prompt surgical removal should be considered in CPC patients with RCPM.
- Subjects :
- Adult
Male
Microbiology (medical)
Antifungal
medicine.medical_specialty
Antifungal Agents
medicine.drug_class
Microbial Sensitivity Tests
macromolecular substances
Candida parapsilosis
Endophthalmitis
Risk Factors
Internal medicine
medicine
Humans
Endocarditis
Aged
Candida
Retrospective Studies
Aged, 80 and over
Cross Infection
biology
business.industry
Mortality rate
Micafungin
Candidemia
General Medicine
Odds ratio
Middle Aged
biology.organism_classification
medicine.disease
Survival Analysis
Surgery
Treatment Outcome
Infectious Diseases
Female
business
Fluconazole
medicine.drug
Subjects
Details
- ISSN :
- 01956701
- Volume :
- 87
- Database :
- OpenAIRE
- Journal :
- Journal of Hospital Infection
- Accession number :
- edsair.doi.dedup.....41864b8cd9e4f2b6fec3e88a7b57a867