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Evaluation of hepatic and kidney dysfunction among newly diagnosed HIV patients with viral hepatitis infection in Cape Coast, Ghana
- Source :
- BMC Research Notes, BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
- Publication Year :
- 2019
-
Abstract
- Objective HIV positive individuals infected with viral hepatitis B (HBV) or C (HCV) are at an increased risk of progression to kidney and liver failures. Therefore, prior to initiation of antiretroviral therapy, early diagnosis and initiation of appropriate treatment protocols are imperative for co-infected individuals. This study evaluated the prevalence of HBV and HCV, and extent of liver and renal dysfunction among 90 newly diagnosed HIV patients attending the Cape Coast Teaching Hospital HIV clinic. Results Levels of alanine aminotransferase, aspartate-platelet ratio index and estimated glomerular filtration rate were used respectively to diagnose hepatotoxicity, liver fibrosis and chronic kidney disease (CKD). Association analyses were evaluated by Pearson’s Chi-square test or Fisher’s exact test and considered significant at p
- Subjects :
- 0301 basic medicine
Liver Cirrhosis
Male
lcsh:Medicine
HIV Infections
Kidney
Gastroenterology
Ghana
0302 clinical medicine
Liver Function Tests
Chronic kidney disease
Prevalence
HBV
030212 general & internal medicine
Stage (cooking)
lcsh:QH301-705.5
Coinfection
virus diseases
Alanine Transaminase
General Medicine
Middle Aged
Hepatitis B
Hepatitis C
Exact test
Research Note
medicine.anatomical_structure
Liver
Female
Viral hepatitis
Glomerular Filtration Rate
Adult
Blood Platelets
medicine.medical_specialty
Renal function
Newly diagnosed
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
Internal medicine
medicine
Humans
Renal Insufficiency, Chronic
lcsh:Science (General)
Aspartic Acid
business.industry
lcsh:R
Hepatotoxicity
HIV
medicine.disease
030104 developmental biology
Cross-Sectional Studies
lcsh:Biology (General)
Hiv patients
business
Clinical proxies
lcsh:Q1-390
Kidney disease
Subjects
Details
- ISSN :
- 17560500
- Volume :
- 12
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC research notes
- Accession number :
- edsair.doi.dedup.....4180b267846a7e9253567527be6daead