Controlled sensory input: A note on the technic of drug evaluation with a preliminary report on a comparative study of sernyl, psilocybin, and LSD-25

Summary Sensory attenuation, a modified form of sensory deprivation where sensory inputs are controlled, is described as a method useful for the study of drug responses. The above is a preliminary report about a comparative study, using this technic, of the following three psychotomimetic drugs: o 1. Sernyl 1—(1-phenylcyclohexyl) piperidine monohydrochloride (May and Baker CI395) 2. Psilocybin, a tryptamine derivative: isolated active principle of Psilocybe Mexicana Heim, a Mexican mushroom. (Sandoz) 3. LSD-25, D. lysergic acid diethylamide. (Sandoz)