Back to Search Start Over

How nuclear data collected for medical radionuclides production could constrain nuclear codes

Authors :
Charlotte Remy
C. Duchemin
Arnaud Fardin
Etienne Nigron
Arnaud Guertin
Ferid Haddad
Corentin Guigot
Vincent Métivier
Nathalie Michel
Laboratoire de physique subatomique et des technologies associées (SUBATECH)
Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST)
Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique)
Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
Accélérateur pour la Recherche en Radiochimie et Oncologie [Nantes Atlantique] (GIP ARRONAX)
Université de Nantes (UN)-Institut de Cancérologie de l'Ouest [Angers/Nantes] (UNICANCER/ICO)
UNICANCER-UNICANCER-Hôpital Guillaume-et-René-Laennec [Saint-Herblain]
ARRONAX - (GIP) Groupement d'Intérêt Public [Saint-Herblain] (Institut de Recherche Public)
ANR-11-EQPX-0004,ARRONAXPLUS,Nucléaire pour la Santé(2011)
ANR-11-LABX-0018,IRON,Radiopharmaceutiques Innovants en Oncologie et Neurologie(2011)
Source :
EPJ Web of Conferences, EPJ Web of Conferences, EDP Sciences, 2017, 146, pp.08008. ⟨10.1051/epjconf/201714608008⟩, EPJ Web of Conferences, Vol 146, p 08008 (2017)
Publication Year :
2017
Publisher :
HAL CCSD, 2017.

Abstract

International audience; The aim of this article is to give the status of nuclear data collected in the framework of the production of innovative radionuclides for therapy and diagnosis applications in collaboration with the GIP ARRONAX, which possesses a multi-particle high energy cyclotron, and to show constrains that can be put on nuclear codes. In order to assess the cross section of a given production route, experiments have been carried out using the stacked-foil technique and gamma-spectroscopy for a set of radionuclides of medical interest: photon (Tc-99m) and positon (Sc-44g) emitters for diagnosis, electron (Re-186g, Tb-155, Sn-117m) and alpha particle (Th-226, Ra-233, Bi-213) emitters for therapeutic applications. A systematic comparison has been performed between the results from the TALYS code (version 1.6) and the large set of data collected using different projectiles (proton, deuteron and alpha particle) from few MeV up to 70 MeV and covering a wide range of target masses. A better overall agreement with our experimental data has been obtained with a combination of models already included in the TALYS code differing from the default one.

Details

Language :
English
ISSN :
2100014X
Database :
OpenAIRE
Journal :
EPJ Web of Conferences, EPJ Web of Conferences, EDP Sciences, 2017, 146, pp.08008. ⟨10.1051/epjconf/201714608008⟩, EPJ Web of Conferences, Vol 146, p 08008 (2017)
Accession number :
edsair.doi.dedup.....414fa1eb492d71a84c379495080c28be