Evaluation of haematological and serum biochemical profile of propofol induced isoflurane anaesthesia in geriatric dogs premedicated with diazepam and butorphanol

Six geriatric dogs of various breeds belonging to either sex presented for various surgical procedures to Teaching Veterinary Clinical Complex, Mannuthy and University Veterinary Hospital, Kokkalai, were selected for the study. On the day of surgery, preanaesthesia was performed with diazepam and butorphanol. After ten minutes of premedication, preoxygenation was carried out for three minutes. Propofol (1 per cent w/v) was administered as a slow bolus, intravenous injection for induction of anaesthesia. Maintenance of surgical plane of anaesthesia was carried out with isoflurane in oxygen using Bain’s circuit system incorporated with isoflurane vapourizer. Haematological and serum biochemical parameters, which were recorded before premedication, ten minutes after commencement of isoflurane and after recovery from general anaesthesia are described here. The present study concluded that the anaesthetic protocol is safe in geriatric animals with regard to haematological and serum biochemical parameters.