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Author Correction: Rapid diagnosis of COVID-19 using FT-IR ATR spectroscopy and machine learning
- Source :
- Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021), Scientific Reports
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- Early diagnosis of COVID-19 in suspected patients is essential for contagion control and damage reduction strategies. We investigated the applicability of attenuated total reflection (ATR) Fourier transform infrared (FTIR) spectroscopy associated with machine learning in oropharyngeal swab suspension fluid to predict COVID-19 positive samples. The study included samples of 243 patients from two Brazilian States. Samples were transported by using different viral transport mediums (liquid 1 or 2). Clinical COVID-19 diagnosis was performed by the RT-PCR. We built a classification model based on partial least squares (PLS) associated with cosine k-nearest neighbours (KNN). Our analysis led to 84% and 87% sensitivity, 66% and 64% specificity, and 76.9% and 78.4% accuracy for samples of liquids 1 and 2, respectively. Based on this proof-of-concept study, we believe this method could offer a simple, label-free, cost-effective solution for high-throughput screening of suspect patients for COVID-19 in health care centres and emergency departments.
- Subjects :
- Adult
Male
2019-20 coronavirus outbreak
Materials science
Time Factors
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Science
Analytical chemistry
Machine Learning
COVID-19 Testing
Spectroscopy, Fourier Transform Infrared
Humans
Fourier transform infrared spectroscopy
Least-Squares Analysis
Spectroscopy
Author Correction
Aged
Multidisciplinary
SARS-CoV-2
COVID-19
Middle Aged
Early Diagnosis
Medicine
Female
Brazil
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 11
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....40f65fc36589dee411c1ee4a95047776