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Author Correction: Rapid diagnosis of COVID-19 using FT-IR ATR spectroscopy and machine learning

Authors :
Luciene Cristina Gastalho Campos
Raquel Lemos Pimentel
Leonardo dos Santos
Valério Garrone Barauna
Wena Dantas Marcarini
Luis Felipe das Chagas e Silva de Carvalho
Paula Frizera Vassallo
Marcelo Saito Nogueira
Matheus Muller
Leonardo Barbosa Leal
Wilson Barros Luiz
José Geraldo Mill
Source :
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021), Scientific Reports
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Early diagnosis of COVID-19 in suspected patients is essential for contagion control and damage reduction strategies. We investigated the applicability of attenuated total reflection (ATR) Fourier transform infrared (FTIR) spectroscopy associated with machine learning in oropharyngeal swab suspension fluid to predict COVID-19 positive samples. The study included samples of 243 patients from two Brazilian States. Samples were transported by using different viral transport mediums (liquid 1 or 2). Clinical COVID-19 diagnosis was performed by the RT-PCR. We built a classification model based on partial least squares (PLS) associated with cosine k-nearest neighbours (KNN). Our analysis led to 84% and 87% sensitivity, 66% and 64% specificity, and 76.9% and 78.4% accuracy for samples of liquids 1 and 2, respectively. Based on this proof-of-concept study, we believe this method could offer a simple, label-free, cost-effective solution for high-throughput screening of suspect patients for COVID-19 in health care centres and emergency departments.

Details

Language :
English
ISSN :
20452322
Volume :
11
Issue :
1
Database :
OpenAIRE
Journal :
Scientific Reports
Accession number :
edsair.doi.dedup.....40f65fc36589dee411c1ee4a95047776