Back to Search Start Over

Magnetic resonance angiography with compressed sensing: An evaluation of moyamoya disease

Authors :
Koji Fujimoto
Takeshi Funaki
Takayuki Yamamoto
Sachi Okuchi
Hikaru Fukutomi
Yutaka Natsuaki
Susumu Miyamoto
Kaori Togashi
Peter Speier
Tomohisa Okada
Yasutaka Fushimi
Akira Yamamoto
Jun Takahashi
Aurélien F. Stalder
Source :
PLoS ONE, PLoS ONE, Vol 13, Iss 1, p e0189493 (2018)
Publication Year :
2018
Publisher :
Public Library of Science, 2018.

Abstract

Compressed sensing (CS) reconstructions of under-sampled measurements generate missing data based on assumptions of image sparsity. Non-contrast time-of-flight MR angiography (TOF-MRA) is a good candidate for CS based acceleration, as MRA images feature bright trees of sparse vessels over a well-suppressed anatomical background signal. A short scan time derived from CS is beneficial for patients of moyamoya disease (MMD) because of the frequency of MR scans. The purpose of this study was to investigate the reliability of TOF-MRA with CS in the evaluation of MMD. Twenty-two patients were examined using TOF-MRA with CS (CS-TOF) and parallel imaging (PI-TOF). The acceleration factors were 3 (CS3) and 5 (CS5) for CS-TOF, and 3 (PI3) for PI-TOF. Two neuroradiologists evaluated the MMD grading according to stenosis/occlusion scores using the modified Houkin’s system, and the visibility of moyamoya vessels (MMVs) using a 3-point scale. Concordance was calculated with Cohen’s κ. The numbers of MMVs in the basal ganglia were compared using Bland-Altman analysis and Wilcoxon’s signed-rank tests. MRA scan times were 4:07, 3:53, and 2:42 for PI3, CS3, and CS5, respectively. CS-reconstruction completed within 10 minutes. MMD grading and MMV visibility scales showed excellent correlation (κ > .966). Although the number of MMVs was significantly higher in CS3 than in PI3 (p < .0001) and CS5 (p < .0001), Bland-Altman analysis showed a good agreement between PI3, CS3, and CS5. Compressed sensing can accelerate TOF-MRA with improved visualization of small collaterals in equivalent time (CS3) or equivalent results in a shorter scan time (CS5).

Details

Language :
English
ISSN :
19326203
Volume :
13
Issue :
1
Database :
OpenAIRE
Journal :
PLoS ONE
Accession number :
edsair.doi.dedup.....40eb354013b7784b4067a183a65a7c74