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No Difference in the Incidence of Malaria in Human-Landing Mosquito Catch Collectors and Non-Collectors in a Senegalese Village with Endemic Malaria
- Source :
- PLoS ONE, PLoS ONE, Public Library of Science, 2015, ⟨10.1371/journal.pone.0126187⟩, PLoS ONE, Vol 10, Iss 5, p e0126187 (2015), Web of Science, PLoS ONE, 2015, e0126187, ⟨10.1371/journal.pone.0126187⟩
- Publication Year :
- 2015
- Publisher :
- HAL CCSD, 2015.
-
Abstract
- International audience; Background The human landing catches is the gold standard method used to study the vectors of malaria and to estimate their aggressiveness. However, this method has raised safety concerns due to a possible increased risk of malaria or other mosquito-borne diseases among the mosquito collectors. The aim of this study was to evaluate the incidence of malaria attacks among mosquito collectors and to compare these results with those of non-collectors in a Senegalese village. Methods From July 1990 to December 2011, a longitudinal malaria study involving mosquito collectors and non-collectors was performed in Dielmo village, Senegal. During the study period, 4 drugs were successively used to treat clinical malaria, and long-lasting insecticide-treated nets were offered to all villagers in July 2008. No malaria chemoprophylaxis was given to mosquito collectors. Incidence of uncomplicated clinical malaria and asymptomatic malaria infection were analyzed among these two groups while controlling for confounding factors associated with malaria risk in random effects negative binomial and logistic regression models, respectively. Results A total of 3,812 person-trimester observations of 199 adults at least 15 years of age were analyzed. Clinical malaria attacks accounted for 6.3% both in collectors and non-collectors, and asymptomatic malaria infections accounted for 21% and 20% in collectors and non-collectors, respectively. A non-significant lower risk of malaria was observed in the collector group in comparison with the non-collector group after adjusting for other risk factors of malaria and endemicity level (Clinical malaria: adjusted incidence rate ratio = 0.89; 95% confidence interval = 0.65-1.22; p= 0.47). Conclusion Being a mosquito collector in Dielmo was not significantly associated with an increased risk of malaria both under holoendemic, mesoendemic and hypoendemic conditions of malaria epidemiology. This result supports the view that HLC, the most accurate method for evaluating malaria transmission, may be used without health concerns in Dielmo.
- Subjects :
- Adult
Male
Veterinary medicine
medicine.medical_specialty
Insecticides
Adolescent
Endemic Diseases
Holoendemic
TRANSMISSION INTENSITY
lcsh:Medicine
Biology
IMMUNITY
Rate ratio
Lower risk
RICE IRRIGATION
RESTING BOXES
SAMPLING METHODS
Chloroquine
CLINICAL MALARIA
Environmental health
Epidemiology
parasitic diseases
HOLOENDEMIC AREA
medicine
otorhinolaryngologic diseases
Animals
Humans
lcsh:Science
WESTERN KENYA
Multidisciplinary
Incidence (epidemiology)
lcsh:R
Middle Aged
medicine.disease
Senegal
3. Good health
Insect Vectors
Malaria
stomatognathic diseases
Culicidae
Chemoprophylaxis
VECTORS
Female
lcsh:Q
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
DAR-ES-SALAAM
medicine.drug
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Database :
- OpenAIRE
- Journal :
- PLoS ONE, PLoS ONE, Public Library of Science, 2015, ⟨10.1371/journal.pone.0126187⟩, PLoS ONE, Vol 10, Iss 5, p e0126187 (2015), Web of Science, PLoS ONE, 2015, e0126187, ⟨10.1371/journal.pone.0126187⟩
- Accession number :
- edsair.doi.dedup.....40e7e7ecee8f012245e312ef344d841c