Association of PTP1B with Outcomes of Breast Cancer Patients who Underwent Neoadjuvant Chemotherapy

Authors :: Luisa G. Villanueva Rodriguez
Alejandra Armengol Alonso
María de la Luz Sevilla González
Braulio Martinez Benitez
Eucario Leon Rodriguez
Monica M. Rivera Franco
Source :: Breast Cancer: Basic and Clinical Research, Vol 10 (2016), Breast Cancer : Basic and Clinical Research, Breast Cancer: Basic and Clinical Research, Vol 2016, Iss 10, Pp 177-184 (2016)
Publication Year :: 2016
Publisher :: SAGE Publishing, 2016.
Abstract: PTP1B is involved in the oncogenesis of breast cancer. In addition, neoadjuvant therapy has been widely used in breast cancer; thus, a measurement to assess survival improvement could be pathological complete response (pCR). Our objective was to associate PTP1B overexpression with outcomes of breast cancer patients who underwent neoadjuvant chemotherapy. Forty-six specimens were included. Diagnostic biopsies were immunostained using anti-PTP1B antibody. Expression was categorized as negative (

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