Back to Search Start Over

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies

Authors :
Luc Djoussé
Graham G. Giles
Maria Lankinen
Cécilia Samieri
Linda Snetselaar
Bruce M. Psaty
Toshiharu Ninomiya
Renata Micha
Yoichiro Hirakawa
Vilmundur Gudnason
Joan Lindsay
Allison M. Hodge
Lyn M. Steffen
Leanne K. Küpers
Jyrki K. Virtanen
Kay-Tee Khaw
Frank Qian
Mackenzie K Senn
Federica Laguzzi
Michael Y. Tsai
Qi Sun
Catherine Helmer
Ingeborg A. Brouwer
Yangbo Sun
Matti Marklund
Wendy Post
William S. Harris
Andres V. Ardisson Korat
Julie K. Bassett
Danielle Laurin
Pierre-Hugues Carmichael
David S. Siscovick
Jennifer G. Robinson
Yun-yu Chen
Johanna M. Geleijnse
Ulf Risérus
Alexis C. Wood
Rebecca D. Jackson
Nicholas J. Wareham
Aleix Sala-Vila
Jaako Mursu
Rachel A. Murphy
Markku Laakso
Jason H Y Wu
Dariush Mozaffarian
Rozenn N. Lemaitre
Nathan L. Tintle
Gudny Eiriksdottir
Fumiaki Imamura
Kuo-Liong Chien
Karin Leander
Nita G. Forouhi
Fatty Acids
Aladdin H. Shadyab
Frank B. Hu
Peilin Shi
Heidi Lai
Tintle, Nathan L [0000-0003-1447-9107]
Imamura, Fumiaki [0000-0002-6841-8396]
Virtanen, Jyrki K [0000-0002-0648-999X]
Forouhi, Nita G [0000-0002-5041-248X]
Geleijnse, Johanna M [0000-0001-7638-0589]
Giles, Graham G [0000-0003-4946-9099]
Gudnason, Vilmundur [0000-0001-5696-0084]
Hodge, Allison [0000-0001-5464-2197]
Laakso, Markku [0000-0002-3394-7749]
Wareham, Nicholas J [0000-0003-1422-2993]
Sun, Qi [0000-0002-8480-1563]
Lemaitre, Rozenn N [0000-0002-7038-1844]
Mozaffarian, Dariush [0000-0001-7958-9492]
Apollo - University of Cambridge Repository
Bordeaux population health (BPH)
Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Tintle, Nathan L. [0000-0003-1447-9107]
Virtanen, Jyrki K. [0000-0002-0648-999X]
Forouhi, Nita G. [0000-0002-5041-248X]
Geleijnse, Johanna M. [0000-0001-7638-0589]
Giles, Graham G. [0000-0003-4946-9099]
Wareham, Nicholas J. [0000-0003-1422-2993]
Lemaitre, Rozenn N. [0000-0002-7038-1844]
Health Sciences
APH - Health Behaviors & Chronic Diseases
APH - Mental Health
Source :
Nature Communications, 12(1), 2329-2329, Fatty Acids and Outcomes Research Consortium (FORCE) 2021, ' Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies ', Nature Communications, vol. 12, 2329, pp. 1-9 . https://doi.org/10.1038/s41467-021-22370-2, Nature Communications, Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2329. ⟨10.1038/s41467-021-22370-2⟩, Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021), Nature Communications 12 (2021) 1, Nature Communications, 12:2329, 1-9. Nature Publishing Group
Publication Year :
2021
Publisher :
Uppsala universitet, Klinisk nutrition och metabolism, 2021.

Abstract

The health effects of omega-3 fatty acids have been controversial. Here we report the results of a de novo pooled analysis conducted with data from 17 prospective cohort studies examining the associations between blood omega-3 fatty acid levels and risk for all-cause mortality. Over a median of 16 years of follow-up, 15,720 deaths occurred among 42,466 individuals. We found that, after multivariable adjustment for relevant risk factors, risk for death from all causes was significantly lower (by 15–18%, at least p<br />Associations between of omega-3 fatty acids and mortality are not clear. Here the authors report that, based on a pooled analysis of 17 prospective cohort studies, higher blood omega-3 fatty acid levels correlate with lower risk of all-cause mortality.

Details

Language :
English
ISSN :
20411723
Database :
OpenAIRE
Journal :
Nature Communications, 12(1), 2329-2329, Fatty Acids and Outcomes Research Consortium (FORCE) 2021, ' Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies ', Nature Communications, vol. 12, 2329, pp. 1-9 . https://doi.org/10.1038/s41467-021-22370-2, Nature Communications, Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2329. ⟨10.1038/s41467-021-22370-2⟩, Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021), Nature Communications 12 (2021) 1, Nature Communications, 12:2329, 1-9. Nature Publishing Group
Accession number :
edsair.doi.dedup.....40c895bcda9ec47ebf585b955f199f41