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Effects of Electrochemical Stimulation of the Ventral Hippocampus on Hypothalamic Electrical Activity and Pituitary Gonadotropin Secretion in Female Rats
- Source :
- Endocrinology. 89:704-713
- Publication Year :
- 1971
- Publisher :
- The Endocrine Society, 1971.
-
Abstract
- Application of an anodal DC electrochemical stimulus to the ventral hippocampus (VHPC) produced changes in the multiple unit activity (MUA) of the arcuate (ARH) and ventromedial hypothalamic nuclei and in tonic and cyclic mechanisms controlling release of pituitary LH in female rats. In ovariectomized estrogen-primed rats, both hypothalamic nuclei responded to VHPC stimulation in less than 6 min with increases in MUA which persisted for hours. The effect was apparently due to the deposition of iron since stainless steel electrodes were effective while platinum electrodes were not. This response was dependent on the presence of an intact medial corticohypothalamic tract, and it did not occur in the dorsomedial hypothalamus, zona incerta or median eminence. Stimulation of the VHPC region which increased ARH neuronal activity also resulted in a significant decrease in plasma LH within 3 hr after its application. Stimulation of the caudate nucleus or mere insertion of electrodes into the VHPC did not lower pl...
- Subjects :
- Ovulation
Hypothalamo-Hypophyseal System
Pituitary gland
medicine.medical_specialty
Hypothalamus
Caudate nucleus
Stimulation
Biology
Hippocampus
Stereotaxic Techniques
Endocrinology
Internal medicine
Electrochemistry
medicine
Animals
Premovement neuronal activity
Castration
Neurons, Afferent
Electrodes
Pentobarbital
Platinum
Luteinizing Hormone
Denervation
Electric Stimulation
Rats
medicine.anatomical_structure
Pituitary Gland
Median eminence
Ovariectomized rat
Zona incerta
Female
Subjects
Details
- ISSN :
- 19457170 and 00137227
- Volume :
- 89
- Database :
- OpenAIRE
- Journal :
- Endocrinology
- Accession number :
- edsair.doi.dedup.....405859dff8e2dfe202f0307cc932cdd7