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Supplementary Figure 3 from A Potent Combination of the Novel PI3K Inhibitor, GDC-0941, with Imatinib in Gastrointestinal Stromal Tumor Xenografts: Long-Lasting Responses after Treatment Withdrawal

Authors :
Patrick Schöffski
Maria Debiec-Rychter
Jonathan A. Fletcher
Christophe M. Deroose
Peter Vermaelen
Jasmien Wellens
Thomas Van Looy
Lori Friedman
Haifu Li
Raf Sciot
Agnieszka Wozniak
Giuseppe Floris
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file - 566K, Xenograft tumor volume assessment, combined for all models. Tumor volume is expressed in percentage, as ratio between time point x baseline. Data are presented for all models (A), based on PTEN protein expression (B), and PTEN status by FISH (C). In GIST-PSW GDC-0941 treatment as single agent lasted 19 days (*). The dotted line shows the time of treatment withdrawal.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....4053728065e986fba8d14c87eb95474c
Full Text :
https://doi.org/10.1158/1078-0432.22450709.v1