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One decade of oral anticoagulation in stroke patients: Results from a large country-wide hospital-based registry
- Source :
- International journal of stroke : official journal of the International Stroke Society. 13(3)
- Publication Year :
- 2017
-
Abstract
- Background New evidence regarding stroke prevention in atrial fibrillation has been published. Implementing knowledge into clinical practice remains challenging. Aims To investigate oral anticoagulants in stroke patients documented in a nationwide registry. Methods The database is an obligatory federal-state-wide hospital-based registry that covers more than 95% of all ischemic strokes, transient ischemic attacks and intracerebral hemorrhages in a community of more than six million inhabitants (Hesse/Germany). We analyzed oral anticoagulants prescribed on discharge in patients with stroke or transient ischemic attack during 2006–2015. Results From 2006 to 2015, we annually selected median 20,895 patients. From 2006 to 2015, the proportion of patients treated with oral anticoagulants increased (9.8% to 24%). The annual proportion of patients with atrial fibrillation remained constant (median: 23%). In atrial fibrillation patients treated with oral anticoagulants, the age increased (median 2008/2009: 76.9 years vs. 2014/2015 79.4 years). The percentage of treated individuals in atrial fibrillation increased dramatically (2006: 30.1% to 2015: 74.5%); in 2015, 30.8% of these patients received vitamin K antagonists and 70.2% new oral anticoagulants. Independent factors associated with new oral anticoagulants therapy were a previous medication with new oral anticoagulants and a treatment on stroke unit. Between new oral anticoagulants- and vitamin K antagonists-treated patients (2015), no differences in age were noted (both mean: 79.4 years). Conclusions The new oral anticoagulants availability enhanced a general trend treating more target patients with oral anticoagulants.
- Subjects :
- Male
Pediatrics
medicine.medical_specialty
Stroke patient
Databases, Factual
Administration, Oral
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Atrial Fibrillation
Outcome Assessment, Health Care
medicine
Medical Staff, Hospital
Humans
In patient
Stroke
Oral anticoagulation
Aged
Retrospective Studies
business.industry
Ischemic strokes
Anticoagulants
Atrial fibrillation
Hospital based
medicine.disease
Neurology
Stroke prevention
Female
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 17474949
- Volume :
- 13
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- International journal of stroke : official journal of the International Stroke Society
- Accession number :
- edsair.doi.dedup.....4040858b28520d6366cca7bc2f3cba8a