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Supplementary Tables 3 - 6 from CCT244747 Is a Novel Potent and Selective CHK1 Inhibitor with Oral Efficacy Alone and in Combination with Genotoxic Anticancer Drugs

Authors :
Michelle D. Garrett
Ian Collins
Suzanne A. Eccles
Florence I. Raynaud
Louis Chesler
John C. Reader
G. Wynne Aherne
Simon P. Robinson
Yann Jamin
Thomas P. Matthews
Michael Lainchbury
Kathy J. Boxall
Elizabeth L. Smith
Albert Hallsworth
Gary Box
Alexis K. De Haven Brandon
Melanie R. Valenti
Angela Hayes
Paul D. Eve
Mike I. Walton
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file, 79K, Supplementary Table 3 - Mouse body weights for data in Figure 4A Body Weights expressed as a percentage of the weight on day 0 for mice bearing HT29 xenografts and treated with gemcitabine (100mg/kg iv), CCT244747 (75mg/kg po) or the combination. Values are mean�SE, n= 3 to 6. Supplementary Table 4 - Mouse body weights for data in Figure 4C Body Weights expressed as a percentage of the weight on day 0 for mice bearing HT29 xenografts and treated with irinotecan (25mg/kg ip), CCT244747 (150mg/kg po) or the combination. Values are mean�SE, n= 3 to 6. Supplementary Table 5 - Mouse body weights for data in Figure 4D Body Weights expressed as a percentage of the weight on day 0 for mice bearing Calu6 xenografts and treated with gemcitabine (100 mg/kg iv), CCT244747 (75mg/kg po) or the combination. Values are mean�SE, n= 3 to 6. Supplementary Table 6 - Mouse body weights for data in Supplementary Table 2 Body Weights expressed as a percentage of the weight on day 0 for mice bearing SW620 xenografts and treated with gemcitabine (100 mg/kg iv), CCT244747 (75mg/kg po) or the combination. Values are mean�SE, n= 3 to 6.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....401ea57b719c1a1d93ab5881aa5484ab
Full Text :
https://doi.org/10.1158/1078-0432.22445615