Evidence of Large Vestibulo-Ocular Reflex Reduction in Patients With Menière Attacks

OBJECTIVE To examine the high frequency horizontal vestibular ocular-reflex (hVOR) during acute attacks of vertigo in Meniere's disease (MD). STUDY DESIGN Retrospective case series and literature review. SETTING Tertiary academic medical center. PATIENTS Patients with clinical diagnosis of unilateral "definite MD." INTERVENTION Review of medical records. MAIN OUTCOME MEASURES Spontaneous nystagmus and the dynamic hVOR gain change at different stages of an acute episode of MD attack. RESULTS We studied 10 vertigo attacks during the unique stages of the episode. During the acme stage of the attack, lower hVOR gain was recorded on the affected side (mean 0.48 ± 0.23), which was associated with a paralytic nystagmus (beating away from the affected ear). Additionally, the mean hVOR gain remained significantly (p