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Peritoneal malignancy: anatomy, pathophysiology and an update on modern day imaging
- Source :
- Br J Radiol
- Publication Year :
- 2022
- Publisher :
- British Institute of Radiology, 2022.
-
Abstract
- With increasing subspecialised experience in radical cytoreductive surgery and intra-abdominal chemotherapy for peritoneal malignancy, outcomes have improved significantly in selected patients. The surgery and the treatment regimens are radical and therefore correct patient selection is critical. The radiologist plays a central role in this process by estimating, as precisely as possible, the pre-treatment disease burden. Because of the nature of the disease process, accurate staging is not an easy task. Tumour deposits may be very small and in locations where they are very difficult to detect. It must be acknowledged that no form of modern day imaging has the capability of detecting the smallest peritoneal nodules, which may only be visible to direct inspection or histopathological evaluation. Nonetheless, it behoves the radiologist to be as exact and precise as possible in the reporting of this disease process. This is both to select patients who are likely to benefit from radical treatment, and just as importantly, to identify patients who are unlikely to achieve adequate cytoreductive outcomes. In this review, we outline the patterns of spread of disease and the anatomic basis for this, as well as the essential aspects of reporting abdominal studies in this patient group. We provide an evidence-based update on the relative strengths and limitations of our available multimodality imaging techniques namely CT, MRI and positron emission tomography/CT.
- Subjects :
- Radical treatment
medicine.medical_specialty
Treatment regimen
business.industry
Cytoreduction Surgical Procedures
Review Article
General Medicine
Disease
Magnetic Resonance Imaging
Peritoneal malignancy
Positron-Emission Tomography
medicine
Humans
Radiology, Nuclear Medicine and imaging
Disease process
Radiology
Patient group
Tomography, X-Ray Computed
Cytoreductive surgery
business
Peritoneal Neoplasms
Disease burden
Subjects
Details
- ISSN :
- 1748880X and 00071285
- Volume :
- 95
- Database :
- OpenAIRE
- Journal :
- The British Journal of Radiology
- Accession number :
- edsair.doi.dedup.....3fec038191218a90ed4673fe3f3b1599