Back to Search
Start Over
Nonmelanoma skin cancer
- Source :
- Current Treatment Options in Oncology. 3:193-203
- Publication Year :
- 2002
- Publisher :
- Springer Science and Business Media LLC, 2002.
-
Abstract
- Therapy for basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) does not end with treatment of the initial lesion because almost 50% of patients with one nonmelanoma skin cancer (NMSC) develop another NMSC in the next 5 years. An integrated program of skin cancer awareness, sun protection, and prophylactic approaches is critical. The risk profile of the tumor influences which therapies and specialties will be involved. Most NMSCs may be treated with outpatient methods. Primary care physicians may treat low-risk tumors, but dermatologists specially trained in cutaneous oncology and a multidisciplinary team should manage high-risk lesions. Superficial BCC and SCC may be treated adequately with superficial modalities such as electrodesiccation and curettage (EDC) and cryotherapy. Topical 5-fluorouracil is effective for small in situ lesions. Invasive but low-risk lesions may be treated with EDC and cryotherapy provided that the tumor is limited to the papillary dermis, is not recurrent, and does not have high-risk features. High-risk tumors are best treated with excision and histologic examination or Mohs micrographic surgery (MMS). MMS is the therapeutic gold standard for all NMSCs in terms of cure rates, margin control, and tissue conservation. Because of its higher cost and specialized process, MMS is best reserved for specific indications.
- Subjects :
- medicine.medical_specialty
Skin Neoplasms
Sun protection
medicine.medical_treatment
Imiquimod
Cryotherapy
Electrodesiccation and curettage
medicine
Humans
Neoplasm Invasiveness
Pharmacology (medical)
Basal cell carcinoma
Life Style
Radiotherapy
business.industry
Papillary dermis
Actinic keratosis
medicine.disease
Dermatology
Oncology
Carcinoma, Basal Cell
Carcinoma, Squamous Cell
Fluorouracil
Skin cancer
business
Diet Therapy
medicine.drug
Subjects
Details
- ISSN :
- 15346277 and 15272729
- Volume :
- 3
- Database :
- OpenAIRE
- Journal :
- Current Treatment Options in Oncology
- Accession number :
- edsair.doi.dedup.....3fe95da12292c949fb46ed486c4790f1