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Susceptibility weighted imaging (SWI) for evaluating renal dysfunction in type 2 diabetes mellitus: a preliminary study using SWI parameters and SWI-based texture features
- Source :
- Ann Transl Med
- Publication Year :
- 2021
-
Abstract
- BACKGROUND: Susceptibility weighted imaging (SWI) could reflect tissue blood oxygen levels, and then whether it could be used to evaluate renal injury remains to be further studied. This study aimed to examine the performance of SWI parameters and SWI-based texture features in evaluating renal dysfunction of type 2 diabetes mellitus (T2DM). METHODS: Forty-five patients with T2DM were included. With the estimated glomerular filtration rate (eGFR), the patients were divided into non-moderate-severe renal injured group (non-msRI, eGFR >60 mL/min/1.73 m(2)) and moderate-severe renal injured group (msRI, eGFR ≤60 mL/min/1.73 m(2)). The 3 SWI parameters and 16 SWI-based texture features between non-msRI and msRI were compared. The correlation between the parameters and BUN, Scr was analyzed. RESULTS: The signal intensity ratio of the medulla to psoas muscle (MPswi) was significantly lower than the signal intensity ratio of the cortex to psoas muscle (CPswi) in non-msRI and msRI group (t=8.619, 3.483, respectively, P0.05), and AUCs were 0.703–0.854. CMswi was an independent protective factor for msRI (OR =0.026, P=0.003). MPswi and CMswi were correlated with BUN (r=0.416, −0.545, P
Details
- ISSN :
- 23055839
- Volume :
- 8
- Issue :
- 24
- Database :
- OpenAIRE
- Journal :
- Annals of translational medicine
- Accession number :
- edsair.doi.dedup.....3fd7bd16daba614c90d199905ae5d4a1