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An experience of administration of modafinil for excessive daytime sleepiness in a patient with myotonic dystorophy
- Source :
- Rinsho Shinkeigaku. 50:578-580
- Publication Year :
- 2010
- Publisher :
- Societas Neurologica Japonica, 2010.
-
Abstract
- We report the beneficial and adverse effects of modafinil for daytime sleepiness in a 62-year-old female patient with myotonic dystrophy. Although it was effective for excessive daytime sleepiness, orolingual dyskinesia appeared the day following administration of modafinil (100 mg/day), and dyskinesia disturbed her daily life including dental treatment. When modafinil was stopped, dyskinesia was improved. However, excessive daytime sleepiness deteriorated gradually; re-treatment with smaller dosage (50 mg every other day) resulted in partial improvement but aggravation of both dyskinesia and diabetes mellitus. Modafinil should be administered carefully when the patient is older or has complications such as glucose intolerance.
- Subjects :
- Excessive daytime sleepiness
Modafinil
Disorders of Excessive Somnolence
Myotonic dystrophy
Diabetes mellitus
mental disorders
Female patient
otorhinolaryngologic diseases
medicine
Humans
Myotonic Dystrophy
Benzhydryl Compounds
Adverse effect
Orolingual dyskinesia
business.industry
Middle Aged
medicine.disease
Dyskinesia
Anesthesia
Central Nervous System Stimulants
Female
Neurology (clinical)
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 18820654 and 0009918X
- Volume :
- 50
- Database :
- OpenAIRE
- Journal :
- Rinsho Shinkeigaku
- Accession number :
- edsair.doi.dedup.....3fa8590a8550a79f5b8753722f1fe96c