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Automatic detection of valve events by epicardial accelerometer allows estimation of the left ventricular pressure trace and pressure–displacement loop area
- Source :
- Scientific Reports, Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
- Publication Year :
- 2020
-
Abstract
- Measurements of the left ventricular (LV) pressure trace are rarely performed despite high clinical interest. We estimated the LV pressure trace for an individual heart by scaling the isovolumic, ejection and filling phases of a normalized, averaged LV pressure trace to the time-points of opening and closing of the aortic and mitral valves detected in the individual heart. We developed a signal processing algorithm that automatically detected the time-points of these valve events from the motion signal of a miniaturized accelerometer attached to the heart surface. Furthermore, the pressure trace was used in combination with measured displacement from the accelerometer to calculate the pressure–displacement loop area. The method was tested on data from 34 animals during different interventions. The accuracy of the accelerometer-detected valve events was very good with a median difference of 2 ms compared to valve events defined from hemodynamic reference recordings acquired simultaneously with the accelerometer. The average correlation coefficient between the estimated and measured LV pressure traces was r = 0.98. Finally, the LV pressure–displacement loop areas calculated using the estimated and measured pressure traces showed very good correlation (r = 0.98). Hence, the pressure–displacement loop area can be assessed solely from accelerometer recordings with very good accuracy.
- Subjects :
- Correlation coefficient
0206 medical engineering
Cardiology
Hemodynamics
lcsh:Medicine
02 engineering and technology
030204 cardiovascular system & hematology
Accelerometer
Signal
Displacement (vector)
Article
Ventricular Function, Left
03 medical and health sciences
0302 clinical medicine
Dogs
Heart Rate
Accelerometry
Ventricular Pressure
Animals
Closing (morphology)
lcsh:Science
Physics
Multidisciplinary
lcsh:R
Health care
020601 biomedical engineering
Heart Valves
Loop (topology)
Ventricular pressure
lcsh:Q
Biomedical engineering
Subjects
Details
- ISSN :
- 20452322
- Database :
- OpenAIRE
- Journal :
- Scientific Reports, Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
- Accession number :
- edsair.doi.dedup.....3f90ad445595fc81dcce3ba90d96f64f