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Testing the efficacy of INtegral Cognitive REMediation (INCREM) in major depressive disorder: study protocol for a randomized clinical trial
- Source :
- Dipòsit Digital de la UB, Universidad de Barcelona, BMC Psychiatry, Vol 19, Iss 1, Pp 1-8 (2019), Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona, BMC Psychiatry, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname
- Publication Year :
- 2019
- Publisher :
- BioMed Central, 2019.
-
Abstract
- Given the limitation of pharmacological treatments to treat cognitive symptoms in patients with Major Depressive Disorder (MDD), cognitive remediation programs has been proposed as a possible procognitive intervention but findings are not conclusive. This study investigates the efficacy of an INtegral Cognitive REMediation (INCREM) that includes a combination of a Functional Remediation (FR) strategy plus a Computerized Cognitive Training (CCT) in order to improve not only cognitive performance but also the psychosocial functioning and the quality of life. A single blind randomized controlled clinical trial in 81 patients with a diagnosis of MDD in clinical remission or in partial remission. Participants will be randomized to one of three conditions: INCREM (FR + CCT), Psychoeducation plus online games and Treatment As Usual (TAU). Intervention will consist in 12 group sessions, of approximately 110 min once a week. The primary outcome measure will be % of change in psychosocial functioning after treatment measured by the Functional Assessment Short Test (FAST); additionally, number of sick leaves and daily activities will also be recorded as pragmatic outcomes. To our knowledge, this is the first randomized controlled clinical trial using a combination of two different approaches (FR + CCT) to treat the present cognitive deficits and to promote their improvements into a better psychosocial functioning. Clinical Trials NCT03624621 . Date registered 10th of August 2018 and last updated 24th August 2018.
- Subjects :
- Adult
Male
Rehabilitació cognitiva
medicine.medical_specialty
Time Factors
Adolescent
Computerized cognitive training
lcsh:RC435-571
medicine.medical_treatment
law.invention
Study Protocol
Young Adult
03 medical and health sciences
0302 clinical medicine
Clinical Protocols
Randomized controlled trial
law
lcsh:Psychiatry
Psychoeducation
medicine
Humans
Single-Blind Method
030212 general & internal medicine
Depressió psíquica
Depressive Disorder, Major
Depression
business.industry
Cognition
Middle Aged
medicine.disease
Cognitive training
030227 psychiatry
Clinical trial
Psychiatry and Mental health
Treatment Outcome
Functional remediation
Mental depression
Research Design
Cognitive remediation therapy
Quality of Life
Physical therapy
Major depressive disorder
Female
Cognitive remediation
business
Psychosocial
Subjects
Details
- Language :
- English
- ISSN :
- 1471244X
- Database :
- OpenAIRE
- Journal :
- Dipòsit Digital de la UB, Universidad de Barcelona, BMC Psychiatry, Vol 19, Iss 1, Pp 1-8 (2019), Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona, BMC Psychiatry, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname
- Accession number :
- edsair.doi.dedup.....3f808893812d322bbe87f266786379c3