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Primary Cauda Equina Lymphoma Treated with CNS-Centric Approach: A Case Report and Literature Review
- Source :
- Journal of Blood Medicine
- Publication Year :
- 2021
- Publisher :
- Dove, 2021.
-
Abstract
- Primary cauda equina lymphoma is an extremely rare entity previously documented in only 24 reported cases. Primary cauda equina lymphoma represents a subtype of neurolymphomatosis, which occurs when lymphoma cells with neurotropism infiltrate and destroy peripheral nerves, spinal nerve roots, nerve plexuses and cranial nerves. The cauda equina is an anatomic structure located in the lower part of the spinal canal consisting of multiple lumbar and sacral nerve roots. Herein, we report a unique case of primary cauda equina diffuse large B-cell lymphoma presenting as a tumor mass in the lower spinal canal, which was treated with a CNS-centric treatment approach followed by autologous hematopoietic stem cell transplantation.
- Subjects :
- musculoskeletal diseases
Pathology
medicine.medical_specialty
MATRIX chemoimmunotherapy
Nerve root
business.industry
Neurotropism
medicine.medical_treatment
Cranial nerves
Cauda equina
diffuse large B cell cauda equina lymphoma
Case Report
Hematology
Hematopoietic stem cell transplantation
medicine.disease
neurolymphomatosis
Lymphoma
medicine.anatomical_structure
Lumbar
primary cauda equina lymphoma
Medicine
Spinal canal
business
autologous stem cell transplant
Subjects
Details
- Language :
- English
- ISSN :
- 11792736
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Journal of Blood Medicine
- Accession number :
- edsair.doi.dedup.....3f5d5a82468cd623dcc934b02723f6c9